Cash and his wife, June Carter Cash, lived in the 13,880-square-foot home from the late 1960s until their deaths in 2003.
"So many prominent things and prominent people in American history took place in that house everyone from Billy Graham to Bob Dylan went into that house," said singer Marty Stuart, who lives next door and was married to Cash's daughter, Cindy, in the 1980s.
Stuart said the man who designed the house, Nashville builder Braxton Dixon, was "the closest thing this part of the country had to Frank Lloyd Wright."
When Cash moved there, the road was a quiet country lane that skirts Old Hickory Lake. Kris Kristofferson, then an aspiring songwriter, once landed a helicopter on Cash's lawn to pitch him a song. Roy Orbison was his next-door neighbor for a while. Parts of the landmark video for Cash's song "Hurt" was shot inside the house.