The tournament is being held to raise money to buy children at St. Jude Nintendo DS Lites and games.
It's the kick-off event for the Gamers for Life charity.
Entry fees are: $20 to play, $5 to watch, with all proceeds going to help the cause. Four games will be played: Tekken 5, Street Fighter 3: Third Strike, Halo 2, and Gears of War.
(Parental consent forms are needed for those under 17 wanting to play Halo 2 or Gears of War. Consent forms and other information on the event can be found at the Gamers for Life website.